Description

2-Allyl-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidin-3(2H)-One is a high-purity, heterocyclic organic compound with the CAS number 955368-90-8, serving as a critical advanced intermediate in modern pharmaceutical and agrochemical research. Its unique pyrazolopyrimidine scaffold, functionalized with allyl and methylthio groups, makes it a versatile building block for the synthesis of novel bioactive molecules. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, particularly in the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block in structure-activity relationship (SAR) studies and lead optimization programs.
• Agrochemical Synthesis: Employed in the research and development of new active ingredients for crop protection products.
• Chemical Biology Probes: Serves as a starting material for creating specialized probes to study enzyme function and cellular signaling processes.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A critical component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Item	Details
Product Name	2-Allyl-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidin-3(2H)-One
CAS No.	955368-90-8
Molecular Formula	C9H10N4OS
Molecular Weight	222.27 g/mol
Synonyms	2-Allyl-6-(methylthio)-2,3-dihydro-1H-pyrazolo[3,4-d]pyrimidin-3-one; 6-(Methylthio)-2-(2-propen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one; 2-Allyl-6-methylsulfanyl-1H-pyrazolo[3,4-d]pyrimidin-3-one; 955368-90-8; Pyrazolo[3,4-d]pyrimidin-3(2H)-one, 2-allyl-6-(methylthio)-
EINECS	Contact for details

Quality Control

Every batch of 2-Allyl-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidin-3(2H)-One is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of research and pre-clinical development. A detailed Certificate of Analysis (COA) with batch-specific data from techniques including HPLC, NMR, and MS is provided with each shipment to guarantee reliable performance and traceability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.