Description

2-Chloro-4-(tert-Butoxycarbonyl-Methylamino)Pyrimidine is a high-value, protected pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its primary commercial value lies in its role as a key intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex molecular architectures with precision.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the pyrimidine core is a key pharmacophore.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and process chemistry optimization in laboratory settings.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring specific heterocyclic structures.
• Building Block for Nucleoside Analogues: Facilitates the creation of modified nucleosides for biochemical and therapeutic applications.

Basic Information

Product Name	2-Chloro-4-(tert-Butoxycarbonyl-Methylamino)Pyrimidine
CAS No.	955112-52-4
Molecular Formula	C11H16ClN3O2
Molecular Weight	257.72 g/mol
Synonyms	2-Chloro-4-[(2-methylpropan-2-yl)oxycarbonyl(methyl)amino]pyrimidine; 4-[(tert-Butoxycarbonyl)(methyl)amino]-2-chloropyrimidine; 2-Chloro-4-(N-Boc-N-methylamino)pyrimidine; 2-Chloro-4-(N-methyl-N-Boc-amino)pyrimidine; Boc-Protected 2-Chloro-4-(Methylamino)Pyrimidine; tert-Butyl 2-chloropyrimidin-4-yl(methyl)carbamate
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(tert-Butoxycarbonyl-Methylamino)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.