Description

4-Oxo-n-{2-[(Pyridin-2-Ylcarbonyl)Amino]Ethyl}-3,4-Dihydroquinazoline-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is valued for its role as a key building block in the synthesis of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is essential for medicinal chemists and pharmaceutical manufacturers engaged in developing kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinazoline and pyridine-based drug candidates.
• Kinase Inhibitor Research: Serves as a core scaffold for the development of targeted therapies in oncology and inflammatory diseases.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Biochemical Research: Employed as a reference standard or tool compound in enzymatic and cellular assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied for custom synthesis and scale-up projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory drug discovery programs.

Basic Information

Product Name	4-Oxo-n-{2-[(Pyridin-2-Ylcarbonyl)Amino]Ethyl}-3,4-Dihydroquinazoline-2-Carboxamide
CAS No.	954346-88-4
Molecular Formula	C₁₈H₁₇N₅O₃
Molecular Weight	351.36 g/mol
Synonyms	N-(2-((Pyridine-2-carbonyl)amino)ethyl)-4-oxo-3,4-dihydroquinazoline-2-carboxamide; 2-Quinazolinecarboxamide, N-[2-[(2-pyridinylcarbonyl)amino]ethyl]-3,4-dihydro-4-oxo-; 954346-88-4; 4-Oxo-N-(2-(pyridine-2-carboxamido)ethyl)-3,4-dihydroquinazoline-2-carboxamide
EINECS	Contact for details

Quality Control

Our 4-Oxo-n-{2-[(Pyridin-2-Ylcarbonyl)Amino]Ethyl}-3,4-Dihydroquinazoline-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.