Description

(2-Amino-3-Fluoro-Phenyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected aniline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a reactive amino group protected by a Boc (tert-butoxycarbonyl) group and a fluorine substituent, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Organic Synthesis Building Block: The Boc-protected amine allows for selective reactions in multi-step syntheses, making it valuable for constructing complex heterocycles and functionalized aromatics.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials that require fluorinated aromatic components.
• Chemical Biology & Proteomics: Serves as a reagent for modifying peptides or creating activity-based probes where a protected aniline functionality is required.

Basic Information

Product Name	(2-Amino-3-Fluoro-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	954238-78-9
Molecular Formula	C11H15FN2O2
Molecular Weight	226.25 g/mol
Synonyms	tert-Butyl (2-amino-3-fluorophenyl)carbamate; N-Boc-2-amino-3-fluoroaniline; 3-Fluoro-2-((tert-butoxycarbonyl)amino)aniline; 2-((tert-Butoxycarbonyl)amino)-3-fluoroaniline; Boc-2,3-FAA; 2-Amino-3-fluorophenylcarbamic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-2,3-diaminofluorobenzene
EINECS	Contact for details

Quality Control

Every batch of (2-Amino-3-Fluoro-Phenyl)-Carbamic Acid tert-Butyl Ester is produced under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation and to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.