Description

(2-Amino-3-Bromo-Phenyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected aniline derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing functionalized aniline or benzimidazole cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Organic Ligand Preparation: Serves as a starting material for synthesizing specialized ligands used in catalysis and material science.
• Peptidomimetic Research: The protected amino group makes it valuable for constructing non-peptide scaffolds in drug discovery programs.
• Dye and Pigment Intermediate: Utilized in the development of advanced colorants and functional dyes due to its bromo and amino functionalities.
• Cross-Coupling Reactions: Acts as a substrate in Buchwald-Hartwig amination and other palladium-catalyzed cross-coupling reactions to form complex C-N bonds.

Basic Information

Product Name	(2-Amino-3-Bromo-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	954238-73-4
Molecular Formula	C11H15BrN2O2
Molecular Weight	287.16 g/mol
Synonyms	tert-Butyl (2-amino-3-bromophenyl)carbamate; N-Boc-2-amino-3-bromoaniline; 2-Amino-3-bromophenylcarbamic acid 1,1-dimethylethyl ester; 3-Bromo-2-aminophenylcarbamic acid tert-butyl ester; Boc-2-Amino-3-bromoaniline; 1,1-Dimethylethyl N-(2-amino-3-bromophenyl)carbamate; N-(tert-Butoxycarbonyl)-2-amino-3-bromoaniline
EINECS	Contact for details

Quality Control

Our (2-Amino-3-Bromo-Phenyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) with detailed specifications are provided to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.