Description

4-Amino-3-(tert-Butoxycarbonyl-Methyl-Amino)-Benzoic Acid Methyl Ester is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for peptide mimetics and other nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for protease inhibitors and targeted therapies.
• Peptidomimetic Research: Used to construct non-peptide scaffolds that mimic the structure and function of natural peptides for drug discovery.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides and fungicides with specific modes of action.
• Chemical Biology Probes: Employed in the creation of labeled compounds and activity-based probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & Institutional Research: Used in university and government labs for methodological development in organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	4-Amino-3-(tert-Butoxycarbonyl-Methyl-Amino)-Benzoic Acid Methyl Ester
CAS No.	954238-55-2
Molecular Formula	C15H22N2O4
Molecular Weight	294.35 g/mol
Synonyms	Methyl 4-Amino-3-[(2-methylpropan-2-yl)oxycarbonyl(methyl)amino]benzoate; Boc-N(Me)-Anthranilic Acid Methyl Ester; Methyl 3-[(tert-Butoxycarbonyl)(methyl)amino]-4-aminobenzoate; 4-Amino-3-[N-(tert-butoxycarbonyl)-N-methylamino]benzoic Acid Methyl Ester; N-Boc-N-Methyl-3,4-Diaminobenzoic Acid Methyl Ester; 954238-55-2; tert-Butyl methyl(4-amino-3-(methoxycarbonyl)phenyl)carbamate
EINECS	Contact for details

Quality Control

Our production of 4-Amino-3-(tert-Butoxycarbonyl-Methyl-Amino)-Benzoic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and GMP-grade synthesis. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.