Description

2-Cyclopropyl-4-Methylpyrimidine-5-Carboxylic Acid is a high-purity pyrimidine carboxylic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique cyclopropyl-substituted pyrimidine core makes it a valuable building block for constructing complex molecular architectures with targeted biological activity. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors.
• Agrochemical Synthesis: Used as a precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for exploring novel heterocyclic compounds and reaction pathways.
• Material Science: Potential intermediate for the synthesis of specialized ligands, coordination complexes, or organic electronic materials.

Basic Information

Product Name	2-Cyclopropyl-4-Methylpyrimidine-5-Carboxylic Acid
CAS No.	954233-05-7
Molecular Formula	C9H10N2O2
Molecular Weight	178.19 g/mol
Synonyms	5-Carboxy-2-cyclopropyl-4-methylpyrimidine; 2-Cyclopropyl-4-methyl-5-pyrimidinecarboxylic acid; 4-Methyl-2-cyclopropylpyrimidine-5-carboxylic acid; 954233-05-7; 2-Cyclopropyl-4-methylpyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-cyclopropyl-4-methyl-
EINECS	Contact for details

Quality Control

Our production of 2-Cyclopropyl-4-Methylpyrimidine-5-Carboxylic Acid adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and chemical identity. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for assay, purity, and identified impurities. Our quality management system supports traceability and compliance with cGMP principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.