Description

2-Isopropyl-4-Methyl-5-Pyrimidinecarboxylic Acid (Saltdata: Free) is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce complex heterocyclic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the pyrimidine core provides essential bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	2-Isopropyl-4-Methyl-5-Pyrimidinecarboxylic Acid (Saltdata: Free)
CAS No.	954233-00-2
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 2-(1-methylethyl)-4-methyl-; 2-Isopropyl-4-methylpyrimidine-5-carboxylic acid; 4-Methyl-2-isopropyl-5-pyrimidinecarboxylic acid; 2-Isopropyl-4-methyl-5-carboxypyrimidine; 2-(Propan-2-yl)-4-methylpyrimidine-5-carboxylic acid; 954233-00-2 (CAS Name); 2-iPr-4-Me-5-Pyrimidinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Isopropyl-4-Methyl-5-Pyrimidinecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.