Description

[1-(2-Chloropyrimidin-4-Yl)Piperidin-4-Yl]Methanol CAS NO 954228-21-8 is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine-pyrimidine core structure. This compound is critical for the synthesis of targeted small molecule therapeutics, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing kinase inhibitors and other novel drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitor drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Biochemical Tool Compound: Serves as a precursor for creating probes and inhibitors used in biological pathway analysis and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for chemical biology and drug discovery projects.

Basic Information

Item	Detail
Product Name	[1-(2-Chloropyrimidin-4-Yl)Piperidin-4-Yl]Methanol
CAS No.	954228-21-8
Molecular Formula	C10H12ClN3O
Molecular Weight	225.67 g/mol
Synonyms	4-Piperidinemethanol, 1-(2-chloro-4-pyrimidinyl)-; (1-(2-Chloropyrimidin-4-yl)piperidin-4-yl)methanol; 1-(2-Chloropyrimidin-4-yl)piperidine-4-methanol; 4-(Hydroxymethyl)-1-(2-chloropyrimidin-4-yl)piperidine; 954228-21-8
EINECS	Contact for details

Quality Control

Our [1-(2-Chloropyrimidin-4-Yl)Piperidin-4-Yl]Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.