Description

2-Chloro-4-(3,3-Dimethylpiperidin-1-Yl)Pyrimidine is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on novel active ingredients, where its specific substitution pattern enables targeted modifications. Industries requiring sophisticated fine chemical intermediates for drug discovery and specialty chemical manufacturing are the primary users of this material.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyrimidine core for bioactivity.
• Chemical Biology & Proteomics: Serves as a valuable scaffold or linker in the design of chemical probes and molecular tools for studying biological systems.
• Material Science Research: Potential building block for creating specialty polymers, ligands for catalysis, or organic electronic materials due to its aromatic and nitrogen-containing structure.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic chemistry and medicinal chemistry.

Basic Information

Item	Details
Product Name	2-Chloro-4-(3,3-Dimethylpiperidin-1-Yl)Pyrimidine
CAS No.	954227-28-2
Molecular Formula	C11H16ClN3
Molecular Weight	225.72 g/mol
Synonyms	2-Chloro-4-(3,3-dimethyl-1-piperidinyl)pyrimidine; 4-(3,3-Dimethylpiperidin-1-yl)-2-chloropyrimidine; 2-Chloro-4-(3,3-dimethylpiperidino)pyrimidine; 1-(2-Chloropyrimidin-4-yl)-3,3-dimethylpiperidine; 954227-28-2; 2-Chloro-4-(3,3-dimethylpiperidin-1-yl)pyrimidine; 2-Chloro-4-(3,3-dimethyl-1-piperazinyl)pyrimidine (common mis-assignment); 2-Chloro-4-(3,3-dimethylpiperidinyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(3,3-Dimethylpiperidin-1-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.