Description

(2-Pyridin-3-Ylpyrimidin-5-Yl)Methanol CAS NO 954227-06-6 is a high-purity heterocyclic building block featuring a pyridine-pyrimidine core functionalized with a hydroxymethyl group. This compound is of significant value in pharmaceutical and agrochemical research as a versatile intermediate for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize drug candidate properties.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of new crop protection agents and herbicides.
• Ligand Development: Utilized in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Incorporated into molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring this specific heterocyclic scaffold.

Basic Information

Product Name	(2-Pyridin-3-Ylpyrimidin-5-Yl)Methanol
CAS No.	954227-06-6
Molecular Formula	C10H9N3O
Molecular Weight	187.20 g/mol
Synonyms	5-(Hydroxymethyl)-2-(3-pyridinyl)pyrimidine; 2-(Pyridin-3-yl)pyrimidin-5-ylmethanol; (2-(Pyridin-3-yl)pyrimidin-5-yl)methanol; 3-Pyrimidin-5-yl-pyridin-2-yl-methanol; (2-Pyridin-3-yl-pyrimidin-5-yl)-methanol; 5-(Hydroxymethyl)-2-(3-pyridyl)pyrimidine
EINECS	Contact for details

Quality Control

Our (2-Pyridin-3-Ylpyrimidin-5-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development. Certificates of Analysis (COA) documenting purity by HPLC, NMR confirmation, and residual solvent levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.