Description

Ethyl 2-Pyridin-2-Ylpyrimidine-5-Carboxylate is a high-purity heterocyclic building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a key synthon in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is essential for research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop novel therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides, leveraging its heterocyclic core.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: Potential precursor for the development of organic electronic materials and metal-organic frameworks (MOFs) due to its conjugated structure and coordination sites.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects.

Basic Information

Product Name	Ethyl 2-Pyridin-2-Ylpyrimidine-5-Carboxylate
CAS No.	954226-91-6
Molecular Formula	C13H11N3O2
Molecular Weight	241.25 g/mol
Synonyms	Ethyl 2-(pyridin-2-yl)pyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-(2-pyridinyl)-, ethyl ester; 2-(Pyridin-2-yl)pyrimidine-5-carboxylic acid ethyl ester; Ethyl 2-(2-pyridyl)pyrimidine-5-carboxylate; CAS 954226-91-6
EINECS	Contact for details

Quality Control

Our Ethyl 2-Pyridin-2-Ylpyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.