Description

2-Chloro-6-Pentafluoroethyl-Pyrimidine-5-Carboxylic Acid is a high-value fluorinated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and a pentafluoroethyl group, makes it an essential intermediate for creating compounds with enhanced biological activity and unique physicochemical properties. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and CNS-targeted drug discovery programs.
• Agrochemical Synthesis: Serves as a critical precursor in the design and synthesis of next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials where fluorine substitution is desired for stability or performance.
• Chemical Biology & Proteomics: Employed as a building block for creating chemical probes, enzyme inhibitors, and labeled compounds for mechanistic and diagnostic studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Chloro-6-Pentafluoroethyl-Pyrimidine-5-Carboxylic Acid
CAS No.	954226-17-6
Molecular Formula	C7H2ClF5N2O2
Molecular Weight	284.55 g/mol
Synonyms	2-Chloro-6-(pentafluoroethyl)pyrimidine-5-carboxylic acid; 5-Pyrimidinecarboxylic acid, 2-chloro-6-(pentafluoroethyl)-; 954226-17-6; 2-Chloro-6-(1,1,2,2,2-pentafluoroethyl)pyrimidine-5-carboxylic acid; 6-(Pentafluoroethyl)-2-chloropyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Pentafluoroethyl-Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management protocols. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS. Our quality systems ensure traceability and consistency, supporting our commitment to reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its nature as a strong acid/organic solvent, it should be kept separate from incompatible materials such as strong bases and oxidizing agents. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.