Description

4-(Azetidin-3-Yloxy)-Benzoic Acid Ethyl Ester is a high-value pharmaceutical intermediate and organic building block of significant interest in modern synthetic chemistry. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. Pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists need this ester for constructing complex molecular architectures, leveraging its reactive azetidine and ester functionalities for further derivatization.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs focused on protease inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the azetidine moiety can contribute to biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for further chemical transformations, including hydrolysis to the corresponding acid, reduction, or amide coupling reactions.
• Ligand and Catalyst Development: Employed in research for creating novel chiral ligands or organocatalysts due to its defined stereogenic center and functional handles.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or liquid crystals where the benzoic acid derivative structure is required.

Basic Information

Product Name	4-(Azetidin-3-Yloxy)-Benzoic Acid Ethyl Ester
CAS No.	954224-48-7
Molecular Formula	C12H15NO3
Molecular Weight	221.25 g/mol
Synonyms	Ethyl 4-(azetidin-3-yloxy)benzoate; Benzoic acid, 4-(3-azetidinyloxy)-, ethyl ester; 4-(Azetidin-3-yloxy)benzoic acid ethyl ester; 3-(4-Ethoxycarbonylphenoxy)azetidine; AZOB-OEt; 954224-48-7; Ethyl p-(azetidin-3-yloxy)benzoate
EINECS	Contact for details

Quality Control

Our 4-(Azetidin-3-Yloxy)-Benzoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.