Description

4-Chloro-6-Naphthalen-1-Yl-Pyrimidine is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. This compound is valued for its unique pyrimidine-naphthalene hybrid structure, which is critical for imparting specific biological and electronic properties in target molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as an electron-transporting or host material in the fabrication of OLED devices due to its naphthalene-pyrimidine conjugated system.
• Ligand Synthesis: Employed in coordination chemistry for creating novel ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Investigated as a component in the synthesis of organic semiconductors and conductive polymers.

Basic Information

Product Name	4-Chloro-6-Naphthalen-1-Yl-Pyrimidine
CAS No.	954222-16-3
Molecular Formula	C₁₄H₉ClN₂
Molecular Weight	240.69 g/mol
Synonyms	4-Chloro-6-(naphthalen-1-yl)pyrimidine; 6-(1-Naphthyl)-4-chloropyrimidine; 1-(4-Chloropyrimidin-6-yl)naphthalene; 4-Chloro-6-(1-naphthyl)pyrimidine; 4-Chloro-6-naphthalen-1-yl-pyrimidine; 4-Chloro-6-(1-naphthalenyl)pyrimidine; 4-Chloro-6-(naphthalen-1-yl)pyrimidine; 4-Chloro-6-(1-naphthyl)-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Naphthalen-1-Yl-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.