Description

4-Chloro-6-Furan-2-Yl-Pyrimidine CAS NO 954221-04-6 is a high-purity heterocyclic building block featuring a fused pyrimidine and furan ring system. This compound is valued for its role as a critical synthetic intermediate in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Employed in discovery chemistry for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	4-Chloro-6-Furan-2-Yl-Pyrimidine
CAS No.	954221-04-6
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	4-Chloro-6-(2-furyl)pyrimidine; 6-(2-Furyl)-4-chloropyrimidine; 4-Chloro-6-furan-2-ylpyrimidine; 4-Chloro-6-(furan-2-yl)pyrimidine; Pyrimidine, 4-chloro-6-(2-furanyl)-; Furan-2-yl(4-chloropyrimidin-6-yl); 954221-04-6; 4-Chloro-6-(2-furanyl)pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-6-Furan-2-Yl-Pyrimidine undergoes rigorous analytical testing to ensure high purity and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.