Description

2,4-Dichloro-5-Fluoro-6-Methylpyrimidine is a high-purity halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents enhance biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• Material Science Precursor: Employed in the development of specialty chemicals, liquid crystals, and advanced organic materials requiring specific halogenated heterocyclic structures.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and contract manufacturing organizations (CMOs) serving the life sciences sector.

Basic Information

Product Name	2,4-Dichloro-5-Fluoro-6-Methylpyrimidine
CAS No.	954220-98-5
Molecular Formula	C5H3Cl2FN2
Molecular Weight	180.99 g/mol
Synonyms	5-Fluoro-2,4-dichloro-6-methylpyrimidine; 6-Methyl-2,4-dichloro-5-fluoropyrimidine; 2,4-Dichloro-5-fluoro-6-methyl-pyrimidine; 5-Fluoro-6-methyl-2,4-dichloropyrimidine; 2,4-Dichloro-5-fluoro-6-methyl-1,3-diazine; Fluoropyrimidine intermediate
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Fluoro-6-Methylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.