Description

2-Chloro-4-(3,5-Difluoro-Phenyl)-Pyrimidine is a high-value halogenated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its molecular structure, featuring both chloro and difluorophenyl substituents, makes it an essential intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Serves as a core building block for creating novel herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Used in the synthesis of organic ligands for metal-organic frameworks (MOFs) and advanced polymeric materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	2-Chloro-4-(3,5-Difluoro-Phenyl)-Pyrimidine
CAS No.	954218-58-7
Molecular Formula	C10H5ClF2N2
Molecular Weight	226.61 g/mol
Synonyms	2-Chloro-4-(3,5-difluorophenyl)pyrimidine; 4-(3,5-Difluorophenyl)-2-chloropyrimidine; 2-Chloro-4-(3,5-difluorophenyl)pyrimidine; Pyrimidine, 2-chloro-4-(3,5-difluorophenyl)-; 954218-58-7
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-(3,5-Difluoro-Phenyl)-Pyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive research and development applications. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.