Description

Methyl 2-(7-Bromo-4-Methoxy-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)-2-Oxoacetate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical companies, biotechnology research firms, and contract development and manufacturing organizations (CDMOs) engaged in the discovery of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Integral in the construction of the pyrrolopyridine core, a privileged structure found in various biologically active molecules.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biochemical assays and target identification due to its reactive ester and bromo functional groups.
• Contract Manufacturing: Supplied to CDMOs for scale-up and cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	Methyl 2-(7-Bromo-4-Methoxy-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)-2-Oxoacetate
CAS No.	954215-11-3
Molecular Formula	C11H9BrN2O4
Molecular Weight	313.11 g/mol
Synonyms	Methyl 2-(7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate; 7-Bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridine-3-carboxylic acid methyl ester oxoacetate; Methyl (7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)oxoacetate; 954215-11-3; Methyl 7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridine-3-carboxylate, oxo-; 1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid, 7-bromo-4-methoxy-, methyl ester, 2-oxo-
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(7-Bromo-4-Methoxy-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)-2-Oxoacetate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure full traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.