Description

3-{[(3-Fluorophenyl)Methyl]Amino}-1$L^{6}-Thiolane-1,1-Dione is a specialized organosulfur compound featuring a thiolane-1,1-dione (sultone) core substituted with a (3-fluorobenzyl)amino group. This compound matters as a high-value pharmaceutical intermediate or research chemical used in the synthesis of novel bioactive molecules, particularly in medicinal chemistry programs targeting enzyme inhibition. It is primarily needed by R&D teams and process chemists in the pharmaceutical, agrochemical, and advanced material science sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting sulfotransferases or other sulfur-metabolizing enzymes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new inhibitors or modulators of biological pathways.
• Agrochemical Development: Serves as a precursor in creating novel herbicides or fungicides with unique modes of action.
• Chemical Biology Probes: Utilized in the development of activity-based probes for studying enzyme function and localization.
• Material Science Precursor: Potential monomer or additive in the synthesis of specialty polymers with specific electronic or surface properties.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory synthetic chemistry and method development projects.

Basic Information

Product Name	3-{[(3-Fluorophenyl)Methyl]Amino}-1$L^{6}-Thiolane-1,1-Dione
CAS No.	953853-00-4
Molecular Formula	C11H12FNO2S
Molecular Weight	241.28 g/mol
Synonyms	3-[(3-Fluorobenzyl)amino]thiolane-1,1-dione; 1,1-Dioxo-tetrahydro-thiophen-3-yl)-(3-fluoro-benzyl)-amine; N-(3-Fluorobenzyl)-1,1-dioxotetrahydro-3-thiophenamine; 3-[(3-Fluorophenyl)methyl]amino-1λ⁶-thiolane-1,1-dione; (3-Fluorobenzyl)amino-thiolane sulfone; 953853-00-4; (3-Fluoro-benzylamino)-thiolane-1,1-dioxide
EINECS	Contact for details

Quality Control

Our 3-{[(3-Fluorophenyl)Methyl]Amino}-1$L^{6}-Thiolane-1,1-Dione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with customer specifications and research-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.