Description

2-(Cyclopentyloxy)-4-Fluoroaniline is a specialized aromatic amine derivative featuring a cyclopentyl ether and a fluorine substituent. This compound serves as a crucial advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the fluorine atom and aniline core contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers, dyes, and functional materials requiring specific optical or electronic properties.
• Chemical Research & Development: A versatile reagent for introducing the 2-(cyclopentyloxy)-4-fluoroaniline moiety into more complex molecules via reactions such as amide coupling, reductive amination, or diazotization.

Basic Information

Product Name	2-(Cyclopentyloxy)-4-Fluoroaniline
CAS No.	953740-21-1
Molecular Formula	C11H14FNO
Molecular Weight	195.24 g/mol
Synonyms	4-Fluoro-2-(cyclopentyloxy)aniline; 2-(Cyclopentyloxy)-4-fluoro-benzenamine; 4-Fluoro-2-cyclopentyloxyaniline; Benzenamine, 4-fluoro-2-(cyclopentyloxy)-; 2-Cyclopentyloxy-4-fluoroaniline; 4-Fluoro-2-cyclopentoxy aniline; 2-Cyclopentoxy-4-fluoroaniline
EINECS	Contact for details

Quality Control

Our 2-(Cyclopentyloxy)-4-Fluoroaniline is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.