Description

2,2,2-Trifluoroethylamine is a versatile organofluorine building block characterized by its highly reactive primary amine group and trifluoroethyl moiety. This compound matters for its ability to introduce fluorine atoms and amine functionality into target molecules, significantly altering their physicochemical properties. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of advanced intermediates, active ingredients, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, including protease inhibitors and bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies.
• Polymer Modification: Employed to introduce fluorinated amine groups into polymers, improving surface properties and chemical resistance.
• Cross-coupling Reagents: Acts as a reactant in palladium-catalyzed amination and other coupling reactions.
• Protecting Group Chemistry: Utilized in sophisticated multi-step organic synthesis protocols.

Basic Information

Product Name	2,2,2-Trifluoroethylamine
CAS No.	753-90-2
Molecular Formula	C2H4F3N
Molecular Weight	99.05 g/mol
Synonyms	2,2,2-Trifluoroethanamine; 2,2,2-Trifluoroethylamine Hydrochloride (salt form); Trifluoroethylamine; 1-Amino-2,2,2-trifluoroethane; 2-Amino-1,1,1-trifluoroethane; α,α,α-Trifluoroethylamine; TFA; TFEA
EINECS	212-037-7

Quality Control

Our 2,2,2-Trifluoroethylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and product traceability.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, away from heat and ignition sources. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.25 g/mL
Boiling Point	~36-38°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.