Description

8-Bromo-2-Chloro-6-Fluoro-Quinazoline is a high-purity, multi-halogenated quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogen substitution pattern, which provides distinct reactivity and electronic properties for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used to develop novel herbicides and fungicides by acting as a core scaffold for bioactive molecules.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials and liquid crystals.
• Chemical Biology: Employed as a probe or labeling reagent due to its reactive halogen sites for bioconjugation.
• Academic & Contract Research: Essential for methodological development and structure-activity relationship (SAR) studies in organic and medicinal chemistry.
• Custom Synthesis: A versatile starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	8-Bromo-2-Chloro-6-Fluoro-Quinazoline
CAS No.	953039-63-9
Molecular Formula	C8H3BrClFN2
Molecular Weight	275.48 g/mol
Synonyms	8-Bromo-2-chloro-6-fluoroquinazoline; 6-Fluoro-8-bromo-2-chloroquinazoline; Quinazoline, 8-bromo-2-chloro-6-fluoro-; 2-Chloro-8-bromo-6-fluoroquinazoline; 8-Bromo-6-fluoro-2-chloroquinazoline; 6-Fluoro-2-chloro-8-bromoquinazoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-Chloro-6-Fluoro-Quinazoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.