Description

2-Chloro-7-Methoxyquinazoline is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive chloro and methoxy substituents, which make it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the quinazoline scaffold's bioactivity.
• Material Science: Serves as a building block for creating organic electronic materials and advanced polymers with specific optical or electronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the quinazoline moiety into more complex structures.
• Academic & R&D: Essential for medicinal chemistry programs and methodological studies in heterocyclic chemistry within university and corporate laboratories.

Basic Information

Product Name	2-Chloro-7-Methoxyquinazoline
CAS No.	953039-15-1
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	7-Methoxy-2-chloroquinazoline; 2-Chloro-7-methoxy-quinazoline; Quinazoline, 2-chloro-7-methoxy-; 953039-15-1; 2-Chloro-7-methoxyquinazoline; 2-Chloro-7-methoxy-quinazoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-7-Methoxyquinazoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.