Description

6-Bromo-2-Chloro-8-Methoxyquinazoline is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique halogenated methoxyquinazoline structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the quinazoline scaffold.
• Material Science: Serves as a building block for creating organic electronic materials, such as charge-transport layers or luminescent compounds.
• Chemical Biology: Employed as a molecular probe or a tagged fragment in drug discovery for target identification and validation studies.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring specific halogenated heterocycles.
• Academic Research: A valuable reagent for methodological studies in cross-coupling reactions, nucleophilic substitutions, and other transformations of halogenated heteroarenes.

Basic Information

Product Name	6-Bromo-2-Chloro-8-Methoxyquinazoline
CAS No.	953039-14-0
Molecular Formula	C9H6BrClN2O
Molecular Weight	273.51 g/mol
Synonyms	8-Methoxy-6-bromo-2-chloroquinazoline; 2-Chloro-6-bromo-8-methoxyquinazoline; 6-Bromo-2-chloro-8-methoxy-quinazoline; Quinazoline, 6-bromo-2-chloro-8-methoxy-; 953039-14-0; SCHEMBL2180627; BRN 12524251
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Chloro-8-Methoxyquinazoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.