Description

4-Piperidineacetic Acid, 1-(4-Fluorobenzoyl)-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Neurological Research: Used in the development of compounds targeting specific receptors within the central nervous system.
• Process Chemistry: Serves as a versatile synthon for scaling up the production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for exploratory synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Piperidineacetic Acid, 1-(4-Fluorobenzoyl)-, Methyl Ester
CAS No.	952949-82-5
Molecular Formula	C15H18FNO3
Molecular Weight	279.31 g/mol
Synonyms	Methyl 1-(4-Fluorobenzoyl)piperidine-4-acetate; 1-(4-Fluorobenzoyl)-4-piperidineacetic Acid Methyl Ester; 4-Piperidineacetic Acid, 1-(4-Fluorobenzoyl)-, Methyl Ester; 1-(p-Fluorobenzoyl)piperidine-4-acetic Acid Methyl Ester; Methyl 1-(p-Fluorobenzoyl)-4-piperidylacetate; 952949-82-5; 1-(4-Fluorobenzoyl)piperidine-4-yl-acetic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 4-Piperidineacetic Acid, 1-(4-Fluorobenzoyl)-, Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the exacting requirements of our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.