Description

3',5'-Di-o-Benzoyl-2'-Deoxy-2'-Fluoro-5-Fluoro-Arabinouridine is a high-purity, fluorinated nucleoside derivative that serves as a critical advanced intermediate in pharmaceutical synthesis. This compound is essential for researchers and manufacturers developing novel antiviral and anticancer therapeutics, particularly those targeting viral polymerases. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical producers requiring highly specific building blocks for complex molecular construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analog antiviral drugs.
• Antiviral Drug Research: Used in the development of therapeutics targeting viruses such as hepatitis and influenza.
• Oncology Research: Serves as a building block for experimental anticancer agents that interfere with DNA/RNA synthesis.
• Biochemical Probe Development: Utilized in creating labeled compounds for studying enzyme mechanisms and metabolic pathways.
• Process Chemistry & Scale-Up: Employed in the optimization and commercial-scale production of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	3',5'-Di-o-Benzoyl-2'-Deoxy-2'-Fluoro-5-Fluoro-Arabinouridine
CAS No.	952651-49-9
Molecular Formula	C24H18F2N2O7
Molecular Weight	484.41 g/mol
Synonyms	2'-Deoxy-2'-fluoro-5-fluoroarabinouridine 3',5'-dibenzoate; 2'-F-5-F-AraU 3',5'-DiOBz; 5-Fluoro-2'-deoxy-2'-fluoroarabinouridine 3',5'-dibenzoate; 2'-Fluoro-5-fluoroarabinofuranosyluracil 3',5'-dibenzoate; FMAU 3',5'-Dibenzoate (ambiguous); 952651-49-9; 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-5-fluorouridine
EINECS	Contact for details

Quality Control

Our production of 3',5'-Di-o-Benzoyl-2'-Deoxy-2'-Fluoro-5-Fluoro-Arabinouridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.