Description

2-{[4-(Pyridin-2-Yl)Piperazin-1-Yl]Methyl}-6-(Thiophen-2-Yl)Pyridazin-3(2H)-One is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is valued for its role as a key building block in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery pipelines. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in vitro and in vivo to study enzyme inhibition, receptor binding, and other pharmacological mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs) for clinical trials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	2-{[4-(Pyridin-2-Yl)Piperazin-1-Yl]Methyl}-6-(Thiophen-2-Yl)Pyridazin-3(2H)-One
CAS No.	952482-19-8
Molecular Formula	C19H19N5OS
Molecular Weight	365.45 g/mol
Synonyms	6-(Thiophen-2-yl)-2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}pyridazin-3(2H)-one; 2-({4-(Pyridin-2-yl)piperazin-1-yl}methyl)-6-(thiophen-2-yl)pyridazin-3(2H)-one; 952482-19-8; 6-(2-Thienyl)-2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-3(2H)-pyridazinone
EINECS	Contact for details

Quality Control

Our production of 2-{[4-(Pyridin-2-Yl)Piperazin-1-Yl]Methyl}-6-(Thiophen-2-Yl)Pyridazin-3(2H)-One adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.