Description

2,4(1H,3H)-Pyrimidinedione, 3-Benzoyl-1-(4-Chlorobutyl)-5-(2-Methyl-3-Pyridinyl)- is a high-value, synthetically derived pyrimidinedione derivative with a complex molecular architecture. This compound matters as a critical pharmaceutical intermediate or research chemical for the development of novel active ingredients, particularly in medicinal chemistry. It is primarily needed by R&D laboratories, custom synthesis providers, and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of potential drug candidates, especially for central nervous system (CNS) or antiviral targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic properties of new chemical entities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of clinical trial materials.
• Biochemical Research: May be utilized as a reference standard or a tool compound in biochemical assays to study enzyme inhibition or receptor binding.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis projects and the development of new synthetic methodologies.

Basic Information

Item	Detail
Product Name	2,4(1H,3H)-Pyrimidinedione, 3-Benzoyl-1-(4-Chlorobutyl)-5-(2-Methyl-3-Pyridinyl)-
CAS No.	952402-46-9
Molecular Formula	C21H20ClN3O3
Molecular Weight	397.85 g/mol
Synonyms	3-Benzoyl-1-(4-chlorobutyl)-5-(2-methylpyridin-3-yl)pyrimidine-2,4(1H,3H)-dione; 1-(4-Chlorobutyl)-3-benzoyl-5-(2-methyl-3-pyridinyl)-2,4(1H,3H)-pyrimidinedione; 952402-46-9; 3-Benzoyl-1-(4-chlorobutyl)-5-(2-methyl-3-pyridinyl)uracil; A potential PDE10A inhibitor intermediate
EINECS	Contact for details

Quality Control

Our 2,4(1H,3H)-Pyrimidinedione derivative is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with complete chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.