Description

Methyl 6-(2-Methoxy-2-Oxoethyl)-4-(4-Methoxyphenyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potential drug candidates, especially those with dihydropyrimidinone cores.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis to develop new therapeutic agents.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for investigating new synthetic methodologies and heterocyclic chemistry.
• Agrochemical Research: Potential application as an intermediate in the development of novel agrochemicals with specific biological activity.

Basic Information

Item	Detail
Product Name	Methyl 6-(2-Methoxy-2-Oxoethyl)-4-(4-Methoxyphenyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	952183-66-3
Molecular Formula	C17H20N2O6
Molecular Weight	348.35 g/mol
Synonyms	Methyl 4-(4-methoxyphenyl)-6-(2-methoxy-2-oxoethyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carbomethoxy-4-(4-methoxyphenyl)-6-(methoxycarbonylmethyl)-3,4-dihydropyrimidin-2(1H)-one; 952183-66-3; Dihydropyrimidinone derivative; Biginelli reaction product; DHPM derivative.
EINECS	Contact for details

Quality Control

We supply this advanced intermediate under a rigorous quality management system. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing analytical results from techniques including HPLC, NMR, and mass spectrometry. Our quality commitment supports compliance with ISO 9001 standards and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.