Description

1,3-Dimethyl-8-(Trifluoromethyl)-1,5-Dihydropyrido[3,2-D]Pyrimidine-2,4,6(3H)-Trione is a high-value, heterocyclic organic compound featuring a fused pyrido-pyrimidine trione core with a strategically positioned trifluoromethyl group. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients. The compound, CAS 952183-38-9, is supplied under stringent quality control to ensure batch-to-batch consistency for demanding synthesis applications.

Application

This specialized chemical serves as a key building block in several high-tech industries. Its primary and potential applications include:

• Pharmaceutical Intermediate: Core scaffold for the research and synthesis of new drug candidates, particularly in oncology, neurology, and antiviral therapeutic areas.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides, leveraging the biological activity of the pyrimidine and trifluoromethyl motifs.
• Medicinal Chemistry & SAR Studies: A crucial precursor for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Chemical Biology Probe Development: Serves as a starting point for creating molecular probes to study specific enzyme targets or biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.
• Academic & Institutional Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	1,3-Dimethyl-8-(Trifluoromethyl)-1,5-Dihydropyrido[3,2-D]Pyrimidine-2,4,6(3H)-Trione
CAS No.	952183-38-9
Molecular Formula	C₁₁H₈F₃N₃O₃
Molecular Weight	287.20 g/mol
Synonyms	8-(Trifluoromethyl)-1,3-dimethyl-1,5-dihydropyrido[3,2-d]pyrimidine-2,4,6(3H)-trione; 1,3-Dimethyl-8-(trifluoromethyl)-3,5-dihydropyrido[3,2-d]pyrimidine-2,4,6-trione; Pyrido[3,2-d]pyrimidine-2,4,6-trione, 1,3-dimethyl-8-(trifluoromethyl)-1,5-dihydro-; 952183-38-9; CAS 952183-38-9
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-8-(Trifluoromethyl)-1,5-Dihydropyrido[3,2-D]Pyrimidine-2,4,6(3H)-Trione is manufactured and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity, purity, and conformity to agreed specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.