Description

{1-[3-(Trifluoromethyl)Benzyl]-1H-1,2,3-Triazol-4-Yl}Methanol is a high-value trifluoromethylated benzyl triazole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a triazole heterocycle with a trifluoromethylphenyl group, enabling precise modulation of physicochemical properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group contributes to improved lipophilicity and biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, or organic electronic materials that require specific fluorine-containing motifs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	{1-[3-(Trifluoromethyl)Benzyl]-1H-1,2,3-Triazol-4-Yl}Methanol
CAS No.	952183-25-4
Molecular Formula	C11H10F3N3O
Molecular Weight	257.21 g/mol
Synonyms	1-[(3-Trifluoromethyl)benzyl]-1H-1,2,3-triazol-4-ylmethanol; 4-(Hydroxymethyl)-1-[(3-trifluoromethyl)benzyl]-1H-1,2,3-triazole; [1-[[3-(Trifluoromethyl)phenyl]methyl]triazol-4-yl]methanol; 1-(3-Trifluoromethylbenzyl)-1H-1,2,3-triazole-4-methanol; (1-((3-(Trifluoromethyl)benzyl)-1H-1,2,3-triazol-4-yl)methanol; 952183-25-4
EINECS	Contact for details

Quality Control

Our {1-[3-(Trifluoromethyl)Benzyl]-1H-1,2,3-Triazol-4-Yl}Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.