Description

2,3,6-Trifluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the benzyl alcohol core, which imparts unique electronic and steric properties critical for modulating the biological activity and physicochemical characteristics of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a key intermediate in the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethylbenzyl moiety can enhance lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a fluorinated precursor in the manufacture of high-performance electronic materials for displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated as a monomer or additive to create specialty polymers with improved chemical resistance, thermal stability, and surface properties.
• Cross-Coupling Reactions: The benzyl alcohol group can be transformed into various functionalities, making it a valuable substrate in palladium-catalyzed cross-coupling reactions for complex molecule assembly.
• Fluorine Chemistry Research: An important standard and starting material in academic and industrial research exploring the effects of selective fluorination on molecular properties.

Basic Information

Product Name	2,3,6-Trifluorobenzyl Alcohol
CAS No.	114152-19-1
Molecular Formula	C7H5F3O
Molecular Weight	162.11 g/mol
Synonyms	(2,3,6-Trifluorophenyl)methanol; 2,3,6-Trifluorobenzylalcohol; 2,3,6-Trifluorobenzenemethanol; α,2,3-Trifluoro-m-tolyl Alcohol; 1-(Hydroxymethyl)-2,3,6-trifluorobenzene; 2,3,6-Trifluorophenylcarbinol
EINECS	Contact for details

Quality Control

Our 2,3,6-Trifluorobenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.