Description

3-Fluorobenzylamine is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine substituent, which can dramatically influence the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral auxiliaries, ligands for asymmetric catalysis, and metal-organic frameworks (MOFs).
• Polymer and Material Science: Incorporated into specialty polymers, epoxy resins, and liquid crystals to modify thermal stability, solubility, and optical properties.
• Fluorescent Probe and Dye Manufacturing: Utilized in the synthesis of fluorophores and molecular probes for bioimaging and diagnostic applications.
• Cross-coupling Reactions: Acts as a valuable amine component in Buchwald-Hartwig amination and other palladium-catalyzed coupling reactions.

Basic Information

Product Name	3-Fluorobenzylamine
CAS No.	100-82-3
Molecular Formula	C7H8FN
Molecular Weight	125.15 g/mol
Synonyms	(3-Fluorophenyl)methanamine; m-Fluorobenzylamine; 3-Fluorobenzenemethanamine; 1-(Aminomethyl)-3-fluorobenzene; α-Amino-3-fluorotoluene; 3-Fluorobenzyl amine; 3-FBA
EINECS	202-892-5

Quality Control

Our 3-Fluorobenzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to minimize moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Density (20°C)	~1.12 g/cm³
Refractive Index (n20D)	~1.525

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.