Description

2-Chloro-6-Fluorobenzylamine is a versatile halogenated benzylamine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive amine group and a halogen-substituted aromatic ring, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.
• Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Polymer Modification: Can be used to introduce functional amine groups into polymer backbones for creating specialty resins and functional materials.

Basic Information

Product Name	2-Chloro-6-Fluorobenzylamine
CAS No.	15205-15-9
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	(2-Chloro-6-fluorophenyl)methanamine; 1-(2-Chloro-6-fluorophenyl)methanamine; 2-Chloro-6-fluoro-benzenemethanamine; α-Amino-2-chloro-6-fluorotoluene; 2-Chloro-6-fluorobenzyl amine; Benzenemethanamine, 2-chloro-6-fluoro-; 2-Chloro-6-fluoro-1-aminomethylbenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluorobenzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its amine functionality and light-sensitive nature, prolonged exposure to air, moisture, or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.