Description

.Beta.-D-Ribo-Hexopyranose, 1,6-Anhydro-3-Deoxy-4-o-(2-Fluorophenyl)Methyl-2-o-Methyl- is a specialized fluorinated carbohydrate derivative with a unique anhydro bridge structure. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of nucleoside analogs, antiviral agents, and other complex therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new bioactive molecules targeting viral polymerases.
• Glycochemistry: Serves as a modified sugar moiety for the synthesis of complex oligosaccharides and glycoconjugates with enhanced stability or specific binding properties.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of fluorinated active pharmaceutical ingredients (APIs).
• Biochemical Probe Synthesis: Used to create labeled or modified nucleotides for studying enzymatic mechanisms and metabolic pathways.
• Fine Chemical Synthesis: A versatile building block for creating fluorinated specialty chemicals with applications in agrochemicals and material science.

Basic Information

Item	Details
Product Name	.Beta.-D-Ribo-Hexopyranose, 1,6-Anhydro-3-Deoxy-4-o-(2-Fluorophenyl)Methyl-2-o-Methyl-
CAS No.	112338-52-0
Molecular Formula	C14H17FO4
Molecular Weight	268.28 g/mol
Synonyms	1,6-Anhydro-3-deoxy-4-O-[(2-fluorophenyl)methyl]-2-O-methyl-β-D-ribo-hexopyranose; 3-Deoxy-4-O-(2-fluorobenzyl)-2-O-methyl-1,6-anhydro-β-D-ribo-hexopyranose; 4-O-(2-Fluorobenzyl)-2-O-methyl-1,6-anhydro-3-deoxy-β-D-ribo-hexopyranose; 2-Fluorobenzyl 2-O-methyl-1,6-anhydro-3-deoxy-β-D-ribo-hexopyranos-4-yl ether; Fluorinated anhydro sugar derivative; 1,6-Anhydro-3-deoxy-4-O-(2-fluorobenzyl)-2-O-methyl-β-D-glucopyranose (common name variant)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support development and cGMP-grade production for pharmaceutical applications, with quality standards tailored to project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.