Description

Ethyl 3-[(5-Bromo-2-Pyrimidinyl)Oxy]-2-Thiophenecarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure combining pyrimidine and thiophene moieties. This compound is critical for research and development in medicinal chemistry, particularly for constructing novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers engaged in the synthesis of complex molecules for drug discovery and crop protection applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its specific molecular architecture.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 3-[(5-Bromo-2-Pyrimidinyl)Oxy]-2-Thiophenecarboxylate
CAS No.	952182-83-1
Molecular Formula	C11H9BrN2O3S
Molecular Weight	329.17 g/mol
Synonyms	Ethyl 5-[(5-bromopyrimidin-2-yl)oxy]thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-[(5-bromo-2-pyrimidinyl)oxy]-, ethyl ester; 5-[(5-Bromopyrimidin-2-yl)oxy]thiophene-2-carboxylic acid ethyl ester; Ethyl 3-(5-bromopyrimidin-2-yloxy)thiophene-2-carboxylate; 952182-83-1; CAS 952182-83-1
EINECS	Contact for details

Quality Control

Our Ethyl 3-[(5-Bromo-2-Pyrimidinyl)Oxy]-2-Thiophenecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.