Description

Methyl 4-(4,4,4-Trifluorobutanoyl)Benzoate is a high-value fluorinated aromatic ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the trifluorobutanoyl moiety, which imparts unique electronic and steric properties essential for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Advanced Polymer Modification: Incorporated into polymer backbones to create specialty materials with enhanced chemical resistance, thermal stability, and unique surface properties.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on various scales.

Basic Information

Product Name	Methyl 4-(4,4,4-Trifluorobutanoyl)Benzoate
CAS No.	952107-73-2
Molecular Formula	C13H13F3O3
Molecular Weight	274.24 g/mol
Synonyms	Benzoic acid, 4-(4,4,4-trifluoro-1-oxobutyl)-, methyl ester; Methyl 4-(4,4,4-trifluorobutanoyl)benzoate; 4-(4,4,4-Trifluorobutanoyl)benzoic acid methyl ester; Methyl p-(4,4,4-trifluorobutanoyl)benzoate; 952107-73-2; Methyl 4'-(trifluorobutanoyl)benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(4,4,4-Trifluorobutanoyl)Benzoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.