Description

2-{4-[(4-Ethoxyphenyl)Carbonyl]Piperazin-1-Yl}-3-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is a high-purity, complex heterocyclic compound with a fused benzothienopyrimidine core, serving as a critical advanced pharmaceutical intermediate. Its molecular architecture, featuring a piperazine linker and an ethoxyphenyl carbonyl group, makes it a valuable scaffold for medicinal chemistry research and the synthesis of novel therapeutic agents. This compound is primarily utilized by R&D laboratories and pharmaceutical manufacturers focused on developing innovative small-molecule drugs, particularly in areas requiring sophisticated chemical building blocks.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Potential precursor in the creation of compounds targeting kinase enzymes, relevant in oncology and inflammatory diseases.
• Chemical Biology Probes: Used to develop molecular probes for studying biological processes and target validation.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	2-{4-[(4-Ethoxyphenyl)Carbonyl]Piperazin-1-Yl}-3-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	951960-48-8
Molecular Formula	C25H28N4O2S
Molecular Weight	448.58 g/mol
Synonyms	2-[4-(4-Ethoxybenzoyl)piperazin-1-yl]-3-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-one; 2-(4-(4-Ethoxybenzoyl)piperazin-1-yl)-3-methyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one; 951960-48-8; Benzothienopyrimidinone piperazine derivative; 4(3H)-Pyrimidinone, 5,6,7,8-tetrahydro-2-[4-[(4-ethoxyphenyl)carbonyl]-1-piperazinyl]-3-methyl[1]benzothieno[2,3-d]-
EINECS	Contact for details

Quality Control

Our production of 2-{4-[(4-Ethoxyphenyl)Carbonyl]Piperazin-1-Yl}-3-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for characterization. Certificates of Analysis (COA) are available upon request and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect this light-sensitive material from prolonged exposure and to minimize moisture uptake. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.