Description

4-Chloro-6,7-Dimethoxy-2-(Trifluoromethyl)Quinazoline is a high-value, multi-functional quinazoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring chloro, dimethoxy, and trifluoromethyl substituents, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinazoline core.
• Material Science: Building block for creating advanced organic electronic materials, such as OLED components or charge-transport materials.
• Chemical Synthesis: Versatile reagent for introducing the 2-(trifluoromethyl)quinazoline moiety into more complex molecular architectures in medicinal and process chemistry.
• Academic & Contract Research: Essential for fundamental research in heterocyclic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	4-Chloro-6,7-Dimethoxy-2-(Trifluoromethyl)Quinazoline
CAS No.	951904-96-4
Molecular Formula	C₁₁H₈ClF₃N₂O₂
Molecular Weight	292.64 g/mol
Synonyms	4-Chloro-6,7-dimethoxy-2-(trifluoromethyl)quinazoline; 2-(Trifluoromethyl)-4-chloro-6,7-dimethoxyquinazoline; 6,7-Dimethoxy-4-chloro-2-trifluoromethylquinazoline; Quinazoline, 4-chloro-6,7-dimethoxy-2-(trifluoromethyl)-; 951904-96-4; 4-Chloro-6,7-bis(methoxy)-2-(trifluoromethyl)quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7-Dimethoxy-2-(Trifluoromethyl)Quinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.