Description

Ethyl 3-Fluoro-2-Methylbenzoylformate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring a fluorinated aromatic core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atom and ester functionality contribute to biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated monomers or additives for advanced polymers, coatings, and liquid crystals to modify physical properties.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Ethyl 3-Fluoro-2-Methylbenzoylformate
CAS No.	951888-55-4
Molecular Formula	C12H13FO3
Molecular Weight	224.23 g/mol
Synonyms	Ethyl 3-Fluoro-2-Methylbenzoylformate; Ethyl 2-(3-Fluoro-2-methylbenzoyl)acetate; 3-Fluoro-2-methylbenzoylformic Acid Ethyl Ester; Ethyl (3-Fluoro-2-methylphenyl)(oxo)acetate; 951888-55-4; Ethyl α-oxo-3-fluoro-2-methylbenzeneacetate; 2-(3-Fluoro-2-methylbenzoyl)acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Fluoro-2-Methylbenzoylformate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality assurance supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.