Description

tert-Butyl 2-Bromo-4-Fluorobenzoate is a high-purity, synthetically valuable benzoate ester derivative. This compound serves as a crucial advanced pharmaceutical intermediate and versatile building block in organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where the 2-bromo-4-fluorobenzoate moiety is required.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers or functionalized molecules for advanced polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new synthetic pathways in medicinal and organic chemistry.

Basic Information

Product Name	tert-Butyl 2-Bromo-4-Fluorobenzoate
CAS No.	951884-50-7
Molecular Formula	C11H12BrFO2
Molecular Weight	275.12 g/mol
Synonyms	2-Bromo-4-fluorobenzoic acid tert-butyl ester; Benzoic acid, 2-bromo-4-fluoro-, 1,1-dimethylethyl ester; tert-Butyl 2-bromo-4-fluorobenzoate; 1,1-Dimethylethyl 2-bromo-4-fluorobenzoate; 2-Bromo-4-fluorobenzoic acid 1,1-dimethylethyl ester; t-Butyl 2-bromo-4-fluorobenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromo-4-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and high-reliability research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.