Description

5-Bromo-4-Ethylpyrimidine is a high-purity brominated pyrimidine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile halogenated scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable building blocks for heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate the pyrimidine core.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Nucleoside Analog Synthesis: A precursor in the development of modified nucleosides and nucleotides for biochemical and antiviral research.
• Ligand and Catalyst Development: Used to create novel nitrogen-containing ligands for transition metal catalysis.

Basic Information

Product Name	5-Bromo-4-Ethylpyrimidine
CAS No.	951884-36-9
Molecular Formula	C6H7BrN2
Molecular Weight	187.04 g/mol
Synonyms	4-Ethyl-5-bromopyrimidine; 5-Bromo-4-ethyl-pyrimidine; Pyrimidine, 5-bromo-4-ethyl-; 951884-36-9
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Ethylpyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.