Description

5-Bromo-4-isopropylpyrimidine is a high-purity halogenated pyrimidine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique substitution pattern, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form more complex biaryl structures.
• Nucleoside Analog Synthesis: A precursor in the modification of nucleoside structures for potential antiviral or anticancer agents.

Basic Information

Product Name	5-Bromo-4-isopropylpyrimidine
CAS No.	951884-28-9
Molecular Formula	C7H9BrN2
Molecular Weight	201.07 g/mol
Synonyms	4-Isopropyl-5-bromopyrimidine; 5-Bromo-4-(1-methylethyl)pyrimidine; 5-Bromo-4-(propan-2-yl)pyrimidine; Pyrimidine, 5-bromo-4-(1-methylethyl)-; 951884-28-9; 5-Br-4-iPr-Pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-isopropylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.