Description

1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-(2,6-Difluorophenyl)- is a high-purity, heterocyclic organic compound featuring a unique pyrrole-pyrimidine core structure with strategic fluorine substitution. This compound matters as a sophisticated pharmaceutical intermediate or research chemical for developing novel active ingredients, particularly in kinase inhibitor and targeted cancer therapy research. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical industries engaged in advanced drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates, especially kinase inhibitors.
• Biochemical Research: Used as a reference standard or probe in enzymatic and cellular assays to study biological pathways.
• Medicinal Chemistry: Core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Chemical Synthesis: Advanced precursor for creating more complex heterocyclic compounds in academic and industrial research.
• API Development: Potential intermediate in the development of Active Pharmaceutical Ingredients (APIs) for targeted therapies.

Basic Information

Product Name	1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-(2,6-Difluorophenyl)-
CAS No.	951784-21-7
Molecular Formula	C15H10F2N4O2
Molecular Weight	316.27 g/mol
Synonyms	5-(2-Amino-4-pyrimidinyl)-2-(2,6-difluorophenyl)-1H-pyrrole-3-carboxylic acid; 2-(2,6-Difluorophenyl)-5-(2-amino-4-pyrimidinyl)-1H-pyrrole-3-carboxylic acid; 951784-21-7; UNII-9I4J8U8U4F; 9I4J8U8U4F; Pyrrole-3-carboxylic acid, 5-(2-amino-4-pyrimidinyl)-2-(2,6-difluorophenyl)-; 1H-Pyrrole-3-carboxylic acid, 5-(2-amino-4-pyrimidinyl)-2-(2,6-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-(2,6-Difluorophenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) with detailed HPLC/LC-MS data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.