Description

1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-(2-Chloro-5-Fluorophenyl)- is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Agrochemical Research: Used in the development of new active ingredients with specific biological activity for crop protection.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular tools to study enzyme function and cellular signaling pathways.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing of complex, high-value specialty chemicals.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for novel heterocyclic chemistry and medicinal chemistry projects.
• Process Chemistry Development: Acts as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.

Basic Information

Product Name	1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-(2-Chloro-5-Fluorophenyl)-
CAS No.	951784-17-1
Molecular Formula	C15H10ClFN4O2
Molecular Weight	332.72 g/mol
Synonyms	5-(2-Amino-4-pyrimidinyl)-2-(2-chloro-5-fluorophenyl)-1H-pyrrole-3-carboxylic acid; 2-(2-Chloro-5-fluorophenyl)-5-(2-aminopyrimidin-4-yl)-1H-pyrrole-3-carboxylic acid; 951784-17-1; Pyrrole-3-carboxylic acid derivative; Kinase inhibitor intermediate; Heterocyclic carboxylic acid building block
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-(2-Chloro-5-Fluorophenyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.