Description

1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-(2-Fluoro-4-Methylphenyl)- is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring fused pyrrole and pyrimidine rings, makes it a critical intermediate for the development of novel pharmacologically active compounds. This high-value chemical is primarily utilized by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of targeted small molecule drugs, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries to explore structure-activity relationships (SAR) and identify new lead candidates.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition or modulate specific biological pathways in early-stage discovery.
• Agrochemical Development: Potential application as an intermediate in the research and synthesis of new-generation crop protection agents.
• Academic & Contract Research: Utilized by universities and CROs (Contract Research Organizations) for fundamental research in heterocyclic chemistry and advanced synthetic methodology development.
• Custom Synthesis: A starting material for the custom manufacturing of complex, non-commercially available molecules for client-specific research projects.

Basic Information

Product Name	1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-(2-Fluoro-4-Methylphenyl)-
CAS No.	951784-15-9
Molecular Formula	C16H13FN4O2
Molecular Weight	312.30 g/mol
Synonyms	5-(2-Amino-4-pyrimidinyl)-2-(2-fluoro-4-methylphenyl)-1H-pyrrole-3-carboxylic acid; 2-(2-Fluoro-4-methylphenyl)-5-(2-amino-4-pyrimidinyl)-1H-pyrrole-3-carboxylic acid; 951784-15-9; Pyrrole-3-carboxylic acid, 5-(2-amino-4-pyrimidinyl)-2-(2-fluoro-4-methylphenyl)-; A potential kinase inhibitor intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and purity suitable for research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment. We support development projects requiring material manufactured under GMP-like conditions for non-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acids/organic solvents. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.