Description

1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-(2-Chloro-4-Fluorophenyl)- is a high-purity, complex heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique molecular scaffold enables the creation of targeted bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty fine chemical industries seeking to develop new therapeutic or crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates, particularly in oncology and antiviral research.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Synthesis: Serves as a core structure for creating molecular probes to study biological pathways and protein interactions.
• Material Science Precursor: Potential intermediate for the synthesis of specialized organic electronic materials or ligands for catalysis.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-directed projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	1H-Pyrrole-3-Carboxylic Acid, 5-(2-Amino-4-Pyrimidinyl)-2-(2-Chloro-4-Fluorophenyl)-
CAS No.	951784-11-5
Molecular Formula	C15H10ClFN4O2
Molecular Weight	332.72 g/mol
Synonyms	5-(2-Amino-4-pyrimidinyl)-2-(2-chloro-4-fluorophenyl)-1H-pyrrole-3-carboxylic acid; 2-(2-Chloro-4-fluorophenyl)-5-(2-amino-4-pyrimidinyl)-1H-pyrrole-3-carboxylic acid; 951784-11-5; 1H-Pyrrole-3-carboxylic acid, 5-(2-amino-4-pyrimidinyl)-2-(2-chloro-4-fluorophenyl)-; Pyrrole-3-carboxylic acid derivative; Chloro-fluoro-phenyl amino-pyrimidinyl pyrrole carboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical parameters are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.