Description

4-Oxo-4H-Quinolizin-9-Yl Trifluoromethanesulfonate is a high-value, specialized chemical intermediate featuring a reactive triflate leaving group. This compound is critical for advanced organic synthesis, particularly in the construction of complex heterocyclic systems and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for its role in facilitating challenging coupling and functionalization reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinolizine and fused heterocyclic compounds with potential biological activity.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science: Serves as a precursor in the creation of organic electronic materials and specialty dyes.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the reactive triflate group.
• Medicinal Chemistry: Employed in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	4-Oxo-4H-Quinolizin-9-Yl Trifluoromethanesulfonate
CAS No.	951624-00-3
Molecular Formula	C₁₄H₈F₃NO₄S
Molecular Weight	343.28 g/mol
Synonyms	9-Quinolizinyl Triflate, 4-Oxo-4H-Quinolizine-9-yl Trifluoromethanesulfonate; 4-Oxo-4H-Quinolizine-9-yl Triflate; 9-Trifluoromethanesulfonyloxy-4H-quinolizin-4-one; 4-Oxo-9-quinolizinyl Trifluoromethanesulfonate; 9-(Trifluoromethanesulfonyloxy)-4H-quinolizin-4-one; 4H-Quinolizin-4-one, 9-[(trifluoromethyl)sulfonyl]oxy]-
EINECS	Contact for details

Quality Control

Our 4-Oxo-4H-Quinolizin-9-Yl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.