Description

Butanedioicacid,2-Hydroxy-,Compd.With7-[(3S,5S)-3-Amino-5-Methyl-1-Piperidinyl]-1-Cyclopropyl-1,4-Dihydro-8-Methoxy-4-Oxo-3-Quinolinecarboxylicacid is a high-purity, non-stoichiometric molecular complex of a fluoroquinolone antibiotic intermediate and succinic acid. This compound is critical for ensuring the stability, bioavailability, and precise formulation of advanced active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories and manufacturers engaged in the synthesis of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel fluoroquinolone-class antibiotics.
• API Salt/Complex Formation: Used to improve the physicochemical properties, such as solubility and crystalline stability, of the parent drug molecule.
• Process Chemistry & Scale-Up: Essential for process development and optimization in cGMP manufacturing environments.
• Analytical Reference Standard: Provides a certified standard for quality control, HPLC, and spectroscopic analysis during API production.
• Formulation Research: Employed in pre-formulation studies to assess compatibility and enhance drug product performance.
• Antibacterial Drug Discovery: Used as a specialized intermediate in medicinal chemistry programs targeting bacterial infections.

Basic Information

Item	Details
Product Name	Butanedioicacid,2-Hydroxy-,Compd.With7-[(3S,5S)-3-Amino-5-Methyl-1-Piperidinyl]-1-Cyclopropyl-1,4-Dihydro-8-Methoxy-4-Oxo-3-Quinolinecarboxylicacid
CAS No.	951163-60-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	7-[(3S,5S)-3-Amino-5-methyl-1-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid compound with 2-hydroxybutanedioic acid; Besifloxacin Succinate Complex; (3S,5S)-7-(3-Amino-5-methylpiperidin-1-yl)-1-cyclopropyl-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid - 2-hydroxysuccinic acid (1:1) complex; Besifloxacin Hydroxysuccinate; Besifloxacin Hemi-Succinate; Antibacterial Intermediate Complex; Quinolone-Succinate Molecular Adduct.
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade products are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for use in API synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.